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EMMC Reports on Byetta's Patient Results 11 Months After FDA ...

... While we agree that there are concerns Byetta will be used as a We run a variety of tests (CGMS, C-Peptide & HBAIC) and are finding that their level of insulin resistance warrants a "pre-diabetic" or diabetic diagnosis.

An area of controversy is the actual definition of pre-diabetes.

The American Diabetes Association in November of 2003 changed the definition of pre-diabetes to one that indicates fasting glucose numbers between 100-125 mil/per DECL.

At EMMC, a combination of tests is recommended to accurately assess an individual's level of insulin resistance (CGMS, CPeptide and HBAIC).

Results of one test alone may not give an accurate assessment of the compromised metabolism.

Eleven months later, Byetta is meeting our expectations for better glucose control and While you may have read that Byetta can cause low blood sugar episodes (hypoglycemia) our patient population is reporting this side effect in small numbers.

To date, Byetta is giving patients better blood sugar control (indicated by CGMS Values) and is stil less likely to cause low blood sugar when compared to insulin.

Approximately 20% of our patients report Byetta cause them to feel nausea.

For some of them, it subsides, but for others, the side effect of nausea will persist, making Byetta a poor choice for them.

The majority of our patients are losing wei...

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